Design a syntéza inhibitorů BCA 2.
BCA 2 (Breast Cancer Associated Protein2) is a novel monomeric RING (Really Interesting New Gene 2) - type ubiquitin E3 ligase. It was found to be overexpressed in 56 % of invasive breast cancers and its expression is correlated with a positive estrogen receptor status. The RING-type family of prote...
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Format: | Dissertation |
Language: | English |
Published: |
2010
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Online Access: | http://www.nusl.cz/ntk/nusl-279113 |