Optimalizace a validace LC/MS metody pro kvantitativní stanovení vybraných diuretik v lidském krevním séru

A new method was developed and fully validated for the quantification of hydrochlorothoazide and chlorthalidone, both diuretic and anti-hypertensive agents, in human serum. This liquid chromatography-tandem mass spectrometry method (LC/MS/MS) is rapid, simple, accurate and selective. The analytes an...

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Bibliographic Details
Main Author: Světlíková, Zuzana
Other Authors: Nobilis, Milan
Format: Dissertation
Language:Czech
Published: 2007
Online Access:http://www.nusl.cz/ntk/nusl-279031