Experimentální použití vybraných cholesterol snižujících léků jako potenciálních faktorů ovlivnění patofyziologie Alzheimerovy nemoci
Rationale: The current standard treatment of Alzheimer's disease (AD) is represented by acetylcholinesterase (AChE) inhibitors. In the pathogenesis of AD, cholesterol is directly involved. Its blood and brain levels positively correlate with amyloid β (Aβ) - a peptide characteristic for AD and...
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| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
2009
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| Online Access: | http://www.nusl.cz/ntk/nusl-275847 |