Molekulárně-dynamické simulace komplexů nukleových kyselin enzymu RNase H

The aim of this diploma thesis was to study interactions between human Rase H enzyme and a natural and modified substrate using molecular dynamics simulations (altogether 9 MD runs ere produced). Conformational preferences of internucleotide linkages (undergoing contacts with the RNase H enzyme) wer...

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Bibliographic Details
Main Author: Bartek, Tomáš
Other Authors: Burda, Jaroslav
Format: Dissertation
Language:Czech
Published: 2009
Online Access:http://www.nusl.cz/ntk/nusl-275477