Geneticky podmíněná variabilita metabolizmu léčiv
Drug metabolism is one of the key processes allowing to eliminate the administered dose. High interindividual variability of the activity of drug metabolizing enzymes is caused by many genetic and epigenetic factors. This variation can result in substantial differences in clinical response to the dr...
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Format: | Doctoral Thesis |
Language: | Czech |
Published: |
2007
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Online Access: | http://www.nusl.cz/ntk/nusl-271400 |