The Synergistic Effects of Combined Hyperthermia and a Nitrosourea in Treatment of a Murine Ependymoblastoma: Some Possible Mechanisms Involved

The effectiveness of heat therapy in combination with 1-(2-chloroethyl)-3-cyclohexyl-l-nitrosourea (CCNU) on a murine ependymoblastoma was investigated. Based on survival time and the number of survivors, whole-body hyperthermia (40°C) increased the therapeutic effectiveness of CCNU. Heat alone did...

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Bibliographic Details
Main Author: Thunning, Claire Ann
Format: Others
Published: NSUWorks 1979
Subjects:
Online Access:http://nsuworks.nova.edu/occ_stuetd/70
http://nsuworks.nova.edu/cgi/viewcontent.cgi?article=1341&context=occ_stuetd