The influence of genetic variation in PSIP1 on HIV-1 infectivity in black South Africans
Genetic variation plays an important role in determining an individual’s susceptibility to infectious disease. PSIP1 encodes LEDGF/p75, which stably associates with the core domain of HIV-1 integrase via a highly-conserved integrase binding domain (IBD) located in its C-terminal. Through this in...
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| Format: | Others |
| Language: | en |
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2010
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| Online Access: | http://hdl.handle.net/10539/7649 |