The effect of metformin-induced AMPK activation on adipogenesis and HIV replication

ABSTRACT Metformin is the most common drug used against type 2 diabetes mellitus. However, it was only recently shown, in human and rat hepatocytes, that metformin-like 5-aminoimidazole-4-carboximide ribonucleoside (AICAR), acts via activation of the AMP-activated protein kinase (AMPK), an enzy...

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Bibliographic Details
Main Author: Alexandre, Kabamba Bankoledi
Format: Others
Language:en
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/10539/4745