The role of integrin a4B7 binding in HIV-1 subtype C pathogenesis in phenotypically variant CD4+ T cell subsets
The integrin α4β7, which mediates the trafficking of T lymphocytes to the gut associated lymphoid tissue (GALT), a site of rapid HIV replication, has been described as an attachment factor for the HIV envelope protein gp120. While differences in binding affinity of early transmitting and chronic gp1...
Main Author: | Richardson, Simone Irene |
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Format: | Others |
Language: | en |
Published: |
2014
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Subjects: | |
Online Access: | http://hdl.handle.net/10539/15236 |
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