The role of integrin a4B7 binding in HIV-1 subtype C pathogenesis in phenotypically variant CD4+ T cell subsets
The integrin α4β7, which mediates the trafficking of T lymphocytes to the gut associated lymphoid tissue (GALT), a site of rapid HIV replication, has been described as an attachment factor for the HIV envelope protein gp120. While differences in binding affinity of early transmitting and chronic gp1...
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Format: | Others |
Language: | en |
Published: |
2014
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Online Access: | http://hdl.handle.net/10539/15236 |