Absence of neurotoxicity and hypernociception in rats administered the antiretroviral drug stavudine

Stavudine (d4T), a nucleoside reverse transcriptase inhibitor (NRTI) used to treat infection by the human immunodeficiency virus (HIV), is associated with the development of peripheral neuropathy and pain in HIV-positive patients. The mechanisms of this toxic neuropathy are poorly understood, primar...

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Bibliographic Details
Main Author: Makweya, Sibongile
Format: Others
Language:en
Published: 2013
Subjects:
HIV
ART
d4T
Online Access:http://hdl.handle.net/10539/12557