Variation in ABCB1 and its effect on immune recovery with antiretrovirals

Ph.D., Faculty of Science, University of the Witwatersrand, 2011 === The ABCB1 gene encodes P-glycoprotein, a transmembrane protein that regulates the efflux of drugs in the cells and may affect the response to antiretroviral drugs. ABCB1 polymorphisms affect the function or expression of P-gp. The...

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Bibliographic Details
Main Author: Du Plooy, Ingrid Marie
Format: Others
Language:en
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10539/11243