In vitro investigation of the ubiquitination and degradation of p53 by Murine Double Minute 2 (MDM2) and Retinoblastoma Binding Protein 6 (RBBP6)

>Magister Scientiae - MSc === P53 is one of the most important tumour suppressor proteins in the body which protects the cell against the tumourigenic effects of DNA damage by initiating processes such as apoptosis, senescence and cell cycle arrest. Regulation of p53 is key — so that the abovemen...

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Bibliographic Details
Main Author: Jooste, Lauren Sarah
Other Authors: Pugh, David J.R.
Language:en
Published: University of the Western Cape 2016
Subjects:
Online Access:http://hdl.handle.net/11394/5051