Improving the inhibitory potency of papaya cystatin, using site-directed mutagenesis

Improving the inhibitory potency of papaya cystatin, using site-directed mutagenesis

Novel conserved amino acid variations of papaya cystatin (PC) were investigated by amino acid substitutions using oryzacystatin-I (OCI) as a model plant cystatin for comparison. These amino acid residues in the conserved motifs are involved in binding with cysteine proteases, these include the GG (G...

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Bibliographic Details
Main Author: Van Wyk, Stefan George
Other Authors: Kunert, Karl J.
Published: 2013
Subjects:
Oryzacystatin
Papaya cystatin
Site-directed mutagenesis
Cysteine protease inhibitor
Inhibitor engineering
UCTD
Online Access:http://hdl.handle.net/2263/28047
Van Wyk, SG, 2011, Improving the inhibitory potency of papaya cystatin, using site-directed mutagenesis, MSc (Biotechnology) dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/28047 >
http://upetd.up.ac.za/thesis/available/etd-09192011-174830/

Internet

http://hdl.handle.net/2263/28047
Van Wyk, SG, 2011, Improving the inhibitory potency of papaya cystatin, using site-directed mutagenesis, MSc (Biotechnology) dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/28047 >
http://upetd.up.ac.za/thesis/available/etd-09192011-174830/

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