Progress towards the stereoselective synthesis of cycleanine.

The emergence of multi-drug resistance (MDR) to antimalarial and anticancer drugs has stimulated a search for novel MDR inhibitors/reversers. Bisbenzylisoquinoline alkaloids (BBIQ) are potential agents for reversing MDR, especially when used as synergistic enhancers of anticancer and antimalarial dr...

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Bibliographic Details
Main Author: Litedu, Eunice Madira.
Other Authors: Van Heerden, Fanie R.
Language:en_ZA
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10413/7982