An investigation into the apoptotic inducing effect of fusaric acid on human lymphocytes and its role in cell growth inhibition.
Fusaric acid (FA) (5-butylpicolinic acid) is a divalent ion chelating agent that has low affinity for Ca2+ and Mg2+ and a high affinity for other essential metal ions such as Fe2+ Mn2+, Zn2+ and Cu2+. Its mode of action therefore may involve its interference with various transition metal ions and th...
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| Language: | en_ZA |
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2012
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| Online Access: | http://hdl.handle.net/10413/7862 |