Synthesis of novel tetrahydroisoquinoline chiral ligands for application in asymmetric transfer hydrogenation.
Several tetrahydroisoquinoline (TIQ) diamine derivatives were prepared for use as ligands in asymmetric transfer hydrogenation (ATH) of acetophenone of which 17 intermediates and the eight target ligands were novel compounds. The initial design followed that of Noyori, who presented the efficiency o...
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| Language: | en |
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2012
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| Online Access: | http://hdl.handle.net/10413/5428 |