INFLUENCE OF SELECTED POLYMORPHISMS ON THE EXPRESSION OF BREAST CANCER IN AFRIKANER BRCA2 CARRIERS
The aim of the study was to elucidate the variation in phenotypic expression observed within BRCA2 c.8162delG mutation positive families. The study attempted to identify possible genetic factors that contribute to the residual risk conferred by the BRCA2 founder mutation. As BC is a polygenetic diso...
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| Format: | Others |
| Language: | en-uk |
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University of the Free State
2012
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| Online Access: | http://etd.uovs.ac.za//theses/available/etd-08232012-144859/restricted/ |