THE SCREENING FOR SINGLE NUCLEOTIDE POLYMORPHISMS OF CYP3A4 IN CHRONIC MYELOGENOUS LEUKEMIA PATIENTS RECEIVING IMATINIB

Chronic myelogenous leukaemia (CML) is a malignant clonal disorder that results in the uncontrolled production of white blood cells. This disease is a result of a reciprocal translocation of the long arms of chromosome 9 and 22 resulting in a shortened chromosome 22, harbouring the BCR-ABL fusion ge...

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Bibliographic Details
Main Author: Lamprecht, G A
Other Authors: Prof CD Viljoen
Format: Others
Language:en-uk
Published: University of the Free State 2010
Subjects:
Online Access:http://etd.uovs.ac.za//theses/available/etd-02152010-151334/restricted/