Synthesis of Mycobacterial Ergothioneine biosynthetic pathway metabolites

Many gram positive bacteria, such as Mycobacterium tuberculosis, lack the redox protective molecule, glutathione and produce mycothiol (MSH) and ergothioneine (ESH) as their principal low molecular mass thiol instead. Ergothioneine has been known for a while as an anti-oxidant; however its role as...

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Bibliographic Details
Main Author: Khonde,Lutete Peguy
Other Authors: Jardine, Anwar
Format: Dissertation
Language:English
Published: University of Cape Town 2014
Online Access:http://hdl.handle.net/11427/6675