Synthesis of Mycobacterial Ergothioneine biosynthetic pathway metabolites
Many gram positive bacteria, such as Mycobacterium tuberculosis, lack the redox protective molecule, glutathione and produce mycothiol (MSH) and ergothioneine (ESH) as their principal low molecular mass thiol instead. Ergothioneine has been known for a while as an anti-oxidant; however its role as...
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Format: | Dissertation |
Language: | English |
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University of Cape Town
2014
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Online Access: | http://hdl.handle.net/11427/6675 |