New aminoquinoline antimalarial cysteine protease inhibitors based on the isatin natural product scaffold
Includes bibliographical references (leaves 120-125). === Many antimalarial drugs including chloroquine are no longer effective against the disease, as their efficacy has been decreased by the spread of drug resistant strains. This loss has been a major barrier to the effective treatment of malaria...
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| Format: | Dissertation |
| Language: | English |
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University of Cape Town
2014
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| Online Access: | http://hdl.handle.net/11427/6352 |