Targeted depletion of RibF, a putative bifunctional FAD synthetase/ flavokinase in Mycobacterium smegmatis using CRISPR interference

Tuberculosis (TB) is the leading killer globally owing to an infectious disease. There is consequently an urgent need to develop novel TB drugs and shorter regimens to treat the causative agent, Mycobacterium tuberculosis, an imperative which demands the identification of new drug targets in essenti...

Full description

Bibliographic Details
Main Author: Raphela, Mabule Lucas
Other Authors: Warner, Digby F
Format: Dissertation
Language:English
Published: Faculty of Health Sciences 2021
Subjects:
TB
Online Access:http://hdl.handle.net/11427/32943