Population pharmacokinetics and pharmacokinetic-pharmacodyamic modeling of antitubercular drugs
Includes abstract. === Includes bibliographical references. === The pharmacokinetics of rifampicin, isoniazid, pyrazinamide and ethambutol in 78 patients with tuberculosis were described using non-linear mixed effects modeling. Pharmacodynamic data was comprised of weekly sputum liquid culture (usin...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Cape Town
2014
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| Online Access: | http://hdl.handle.net/11427/3275 |