Molecular and Kinetic Characteristics of wild type and mutant Porphobilinogen deaminase
The purpose of this dissertation was to provide an overview of acute intermittent porphyria, focussing on the structure and function of the enzyme, porphobilinogen deaminase (PBGD), as well as experimentally demonstrating the use of kinetic, structural and thermodynamic approaches to shed light on t...
Main Author: | |
---|---|
Format: | Dissertation |
Language: | English |
Published: |
Faculty of Health Sciences
2019
|
Subjects: | |
Online Access: | http://hdl.handle.net/11427/30119 |