Proteolytic mechanisms involved in the metastasis of human melanoma cells

The metastatic process requires that tumour cells are capable of traversing various micro-environmental barriers, such as the basement membrane. There are various proteolytic mechanisms which could contribute to the process, plasminogen activation by tissue plasminogen activator (tPA) and urokinase...

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Bibliographic Details
Main Author: Fletcher, Jean Margaret
Other Authors: Dowdle, Eugene B
Format: Dissertation
Language:English
Published: University of Cape Town 2018
Subjects:
Online Access:http://hdl.handle.net/11427/27116