Whole Blood Mitochondrial DNA Depletion in Human Immunodeficiency Virus-Infected Children

Whole Blood Mitochondrial DNA Depletion in Human Immunodeficiency Virus-Infected Children

Background: Nucleoside reverse transcriptase inhibitors (NRTIs) interfere with mitochondrial DNA polymerase gamma causing significant toxic effects, including fatal lactic acidosis. Little is known about mitochondrial DNA (mtDNA) in human immunodeficiency virus (HIV) infected children who face a lif...

Full description

Bibliographic Details
Main Author: van der Watt, George Frederick
Other Authors: Henderson, Howard
Format: Dissertation
Language:English
Published: University of Cape Town 2014
Subjects:
Chemical Pathology
Online Access:http://hdl.handle.net/11427/2705

Internet

http://hdl.handle.net/11427/2705

Similar Items