The role of endotoxin receptors toll-like receptor 4 and lipopolysaccharide-binding protein in Mycobacterium tuberculosis infection
The aim of this study was to investigate the role of PRRs, namely TLR4 and LBP in vivo in the development of an immune response to a Mycobacterium tuberculosis infection. Mice with null mutations of the endotoxin receptors LBP and TLR4 were compared with wild-type mice (PRRs intact) in the context o...
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| Format: | Dissertation |
| Language: | English |
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University of Cape Town
2017
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| Online Access: | http://hdl.handle.net/11427/26514 |