Protein-protein interactions of human somatic angiotensin-converting enzyme

In this study, novel disulphide bridges were engineered into the linker region of ACE [Angiotensin-converting enzyme] in an attempt to limit inter-domain movement, thereby producing a candidate for crystallisation and to determine the effect of these bridges on inter-domain movement.

Bibliographic Details
Main Author: Gordon, Kerry
Other Authors: Sturrock, Edward D
Format: Doctoral Thesis
Language:English
Published: University of Cape Town 2014
Subjects:
Online Access:http://hdl.handle.net/11427/10535