Protein-protein interactions of human somatic angiotensin-converting enzyme
In this study, novel disulphide bridges were engineered into the linker region of ACE [Angiotensin-converting enzyme] in an attempt to limit inter-domain movement, thereby producing a candidate for crystallisation and to determine the effect of these bridges on inter-domain movement.
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Format: | Doctoral Thesis |
Language: | English |
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University of Cape Town
2014
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Online Access: | http://hdl.handle.net/11427/10535 |