The hexosamine biosynthetic pathway induces gene promoter activity of the cardiac-enriched isoform of acetyl-CoA carboxylase
Thesis (PhD)--Stellenbosch University, 2013. === ENGLISH ABSTRACT: The cardiac isoform of acetyl-CoA carboxylase (ACCβ) produces malonyl-CoA, a potent inhibitor of mitochondrial fatty acid (FA) uptake; thus increased ACCβ activity decreases fatty acid utilization thereby potentially leading to intra...
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| Format: | Others |
| Language: | en_ZA |
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Stellenbosch : Stellenbosch University
2013
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| Online Access: | http://hdl.handle.net/10019.1/79957 |