The hexosamine biosynthetic pathway induces gene promoter activity of the cardiac-enriched isoform of acetyl-CoA carboxylase

The hexosamine biosynthetic pathway induces gene promoter activity of the cardiac-enriched isoform of acetyl-CoA carboxylase

Thesis (PhD)--Stellenbosch University, 2013. === ENGLISH ABSTRACT: The cardiac isoform of acetyl-CoA carboxylase (ACCβ) produces malonyl-CoA, a potent inhibitor of mitochondrial fatty acid (FA) uptake; thus increased ACCβ activity decreases fatty acid utilization thereby potentially leading to intra...

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Bibliographic Details
Main Author: Imbriolo, Jamie
Other Authors: Essop, M. Faadiel
Format: Others
Language:en_ZA
Published: Stellenbosch : Stellenbosch University 2013
Subjects:
Insulin resistance
Hexosamine biosynthetic pathway
Fatty acids > Metabolism
Heart > Metabolism
Obesity
Dissertations > Physiology (Human and animal)
Theses > Physiology (Human and animal)
Online Access:http://hdl.handle.net/10019.1/79957

Internet

http://hdl.handle.net/10019.1/79957

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