Synthetic analogues of marine bisindole alkaloids as potent selective inhibitors of MRSA pyruvate kinase

Globally, methicillin resistant Staphylococcus aureus (MRSA) has become increasingly difficult to manage in the clinic and new antibiotics are required. The structure activity relationship (SAR) study presented in this thesis forms part of an international collaborative effort to identify potent and...

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Bibliographic Details
Main Author: Veale, Clinton Gareth Lancaster
Format: Others
Language:English
Published: Rhodes University 2014
Subjects:
Online Access:http://hdl.handle.net/10962/d1020893