Synthetic analogues of marine bisindole alkaloids as potent selective inhibitors of MRSA pyruvate kinase
Globally, methicillin resistant Staphylococcus aureus (MRSA) has become increasingly difficult to manage in the clinic and new antibiotics are required. The structure activity relationship (SAR) study presented in this thesis forms part of an international collaborative effort to identify potent and...
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Format: | Others |
Language: | English |
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Rhodes University
2014
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Online Access: | http://hdl.handle.net/10962/d1020893 |