Allosteric modulation of conformational dynamics in human Hsp90α: a computational study
Central to Hsp90’s biological function is its ability to interconvert between various conformational states. Drug targeting of Hsp90’s regulatory mechanisms, including its modulation by co-chaperone association, presents as an attractive therapeutic strategy for Hsp90 associated pathologies. Here, w...
| Main Authors: | , , |
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| Format: | Others |
| Language: | English |
| Published: |
2017
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| Online Access: | http://hdl.handle.net/10962/68531 http://dx.doi.org/10.1101/198341 |