Fibronectin is a stress responsive gene regulated by HSF1 in response to geldanamycin
Fibronectin is an extracellular matrix glycoprotein with key roles in cell adhesion and migration. Hsp90 binds directly to fibronectin and Hsp90 depletion regulates fibronectin matrix stability. Where inhibition of Hsp90 with a C-terminal inhibitor, novobiocin, reduced the fibronectin matrix, treatm...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2017
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| Online Access: | http://hdl.handle.net/10962/59931 https://doi:10.1038/s41598-017-18061-y |