Design and evaluation of chitosan and N-trimethyl chitosan chloride microspheres for intestinal drug delivery / Johannes Petrus Venter
The absorption enhancing ability of chitosan, a linear polysaccharide, is mediated by protonated amino groups on the C-2 position of the molecules that induce interaction with the anionic sites on the cell membranes to subsequently alter tight junction integrity. In neutral and basic environments, s...
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North-West University
2009
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| Online Access: | http://hdl.handle.net/10394/937 |