Inhibition of monoamine oxidase by selected 8-[(phenylsulfanyl)methyl]caffeine derivatives / Thokozile Okaecwe.
Purpose Monoamine oxidase (MAO) consists of two isoforms, namely MAO-A and MAO-B. Both these isoforms are involved in the oxidation of dopamine. In Parkinson’s disease (PD) therapy, the inhibition of the oxidation of dopamine by MAO may elevate the levels of dopamine in the brain and prevent the gen...
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Language: | en |
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North-West University
2013
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Online Access: | http://hdl.handle.net/10394/9187 |