Urinary 1,4–dihydroxynonene mercapturic acid (DHN–MA) and 8–hydroxy–2'–deoxyguanosine (8–OHdG) as markers of oxidative damage : the SABPA study / by Leandrie Steenkamp

Urinary 1,4–dihydroxynonene mercapturic acid (DHN–MA) and 8–hydroxy–2'–deoxyguanosine (8–OHdG) as markers of oxidative damage : the SABPA study / by Leandrie Steenkamp

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The human body has evolved certain defence mechanisms to cope with the high occurrence of free radicals. These radicals are obtained endogenously from the mitochondria, peroxisomes, the cytochrome P450 (CYP 450) system and neutrophils, or exogenously from the environment. Lack of antioxidants and/or...

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Bibliographic Details
Main Author: Steenkamp, Leandrie
Published: North-West University 2011
Subjects:
Lipid peroxidation
DNA damage
8-hydroxy-2'-deoxyguanosine
1,4-dihydroxynonene mercapturic acid
Tandem mass spectrometry
Lipied peroksidasie
DNS skade
8-hidroksie-2'-deoksieguanosien
1,4 dihidroksienonene merkaptuursuur
Tandem massa spektrometrie
Online Access:http://hdl.handle.net/10394/4559

Internet

http://hdl.handle.net/10394/4559

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