The role of alpha-2A-adrenergic receptor antagonism in therapeutic efficacy and onset of action of antidepressant drugs in a rat model of depression / Nico Liebenberg
While delayed onset of antidepressant action remains a shortcoming of current antidepressants, preliminary clinical data with newer antidepressants, including mirtazapine, show promise for a hastened onset. Several potential mechanisms have been postulated and investigated. Mirtazapine displays sero...
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North-West University
2009
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| Online Access: | http://hdl.handle.net/10394/1414 |