Structural Studies of the Mechanism by Which BCL-2 and Beclin Proteins Regulate Autophagy and Apoptosis

Autophagy and apoptosis are catabolic pathways essential for homeostasis in all eukaryotes. While autophagy usually promotes cell-survival by enabling degradation and recycling of damaged macromolecules, apoptosis is the canonical programmed cell death pathway. Dysfunction of autophagy and apoptosis...

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Bibliographic Details
Main Author: Su, Minfei
Format: Others
Published: North Dakota State University 2018
Online Access:https://hdl.handle.net/10365/27994