Ligand Binding and Catalysis in Selected Sirtuin Isozymes

Due to their intimate roles in survival, longevity as well as pathogenesis via “epigenetic” and “metabolic” regulatory mechanisms, sirtuins have gained considerable interest toward undertaking detailed biochemical/biophysical studies. The present study was designed to ascertain the mechanistic detai...

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Bibliographic Details
Main Author: Yu, Junru
Format: Others
Published: North Dakota State University 2016
Online Access:http://hdl.handle.net/10365/25733