Activation of endogenous full-length active LINE-1 RNA using CRISPR activation to study its role during somatic cell reprogramming

Activation of endogenous full-length active LINE-1 RNA using CRISPR activation to study its role during somatic cell reprogramming

The repetitive sequence composes nearly half of human and mouse genome, most of which are scattered repeats of transposable elements (TEs). The non-LTR retrotransposons are the most accumulated TEs in the mammalian genome and L1s are the most active and abundant autonomous retrotransposons. L1s are...

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Bibliographic Details
Main Author: Alsolami, Amjad
Other Authors: Orlando, Valerio
Language:en
Published: 2021
Subjects:
Transposable elements
LINE-1
Somatic cell reprogramming
Gene editing
CRISPR activation
iPSCs
Online Access:Alsolami, A. (2021). Activation of endogenous full-length active LINE-1 RNA using CRISPR activation to study its role during somatic cell reprogramming. KAUST Research Repository. https://doi.org/10.25781/KAUST-31L5B
http://hdl.handle.net/10754/673787

Internet

Alsolami, A. (2021). Activation of endogenous full-length active LINE-1 RNA using CRISPR activation to study its role during somatic cell reprogramming. KAUST Research Repository. https://doi.org/10.25781/KAUST-31L5B
http://hdl.handle.net/10754/673787

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