Quantifying Localizations and Dynamics in Single Bacterial Cells

Levels of macromolecules fluctuate both spatially and temporally in individual cells. Such heterogeneity could be exploited for bet hedging in uncertain environments, or be suppressed by negative feedback if perturbations are deleterious. For the master stress-response regulator in Escherichia coli,...

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Bibliographic Details
Main Author: Landgraf, Dirk
Other Authors: Paulsson, Johan Martin
Language:en_US
Published: Harvard University 2012
Subjects:
Online Access:http://dissertations.umi.com/gsas.harvard:10612
http://nrs.harvard.edu/urn-3:HUL.InstRepos:9920184