Characterization of the Mamu-A*01-Restricted CD8-Positive T Lymphocyte Immunodominance Hierarchy in Simian Immunodeficiency Virus-Infected Rhesus Monkeys

\(CD8^+\) cytotoxic T lymphocytes (CTLs) play a critical role in controlling human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) replication. The CTL responses that are thought to be the most protective against HIV and SIV are those that are of high frequency, recognize multip...

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Bibliographic Details
Main Author: Osuna-Gutierrez, Christa Elyse
Other Authors: Letvin, Norman
Language:en_US
Published: Harvard University 2012
Subjects:
HIV
SIV
Online Access:http://dissertations.umi.com/gsas.harvard:10600
http://nrs.harvard.edu/urn-3:HUL.InstRepos:9817660