Filopodia-independent roles of the actin bundling protein fascin in promoting cell motility

Fascin is an actin bundling protein whose overexpression has in recent years been systematically linked to increased metastasis and poor outcome in cancer patients. It is well established that fascin expression correlates with enhanced cell migration; however, the underlying mechanisms are poorly un...

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Bibliographic Details
Main Author: Oak, Youbean
Other Authors: Danuser, Gaudenz
Language:en_US
Published: Harvard University 2014
Subjects:
Online Access:http://dissertations.umi.com/gsas.harvard.inactive:11801
http://nrs.harvard.edu/urn-3:HUL.InstRepos:13104236