Single-molecule techniques to probe the dynamic gene regulatory network formed by core pluripotency circuit in embryonic stem cells
This work investigates the dynamics of gene regulatory network formed by Oct4, Sox2 and Nanog in embryonic stem cells (ESCs). Despite a large number of existing studies on stem cells, current technologies used often force a compromise between quantification of gene expression via bulk measurements a...
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| Language: | en_US |
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Harvard University
2014
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| Online Access: | http://dissertations.umi.com/gsas.harvard.inactive:11737 http://nrs.harvard.edu/urn-3:HUL.InstRepos:13070085 |