Optimizing siRNA Efficacy through Alteration in the Target Cell-Adhesion Substrate Interaction

Short interfering RNA (siRNA) is a class of nucleotide drugs with a profound potential to improve patient health through its ability to silence the expression of specific genes at the post-transcriptional level. However, the clinical application of siRNA therapeutics remains hindered by a lack of ef...

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Bibliographic Details
Main Author: Khormaee, Sariah
Format: Others
Language:en
Published: Harvard University 2014
Subjects:
Online Access:http://etds.lib.harvard.edu/hms/admin/view/59
http://nrs.harvard.edu/urn-3:HUL.InstRepos:12407617