Optimizing siRNA Efficacy through Alteration in the Target Cell-Adhesion Substrate Interaction
Short interfering RNA (siRNA) is a class of nucleotide drugs with a profound potential to improve patient health through its ability to silence the expression of specific genes at the post-transcriptional level. However, the clinical application of siRNA therapeutics remains hindered by a lack of ef...
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Format: | Others |
Language: | en |
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Harvard University
2014
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Online Access: | http://etds.lib.harvard.edu/hms/admin/view/59 http://nrs.harvard.edu/urn-3:HUL.InstRepos:12407617 |