Optical control of mammalian endogenous transcription and epigenetic states
The dynamic nature of gene expression enables cellular programming, homeostasis and environmental adaptation in living systems. Dissection of causal gene functions in cellular and organismal processes therefore necessitates approaches that enable spatially and temporally precise modulation of gene e...
Main Author: | Brigham, Mark Daniel |
---|---|
Other Authors: | Zhang, Feng |
Language: | en_US |
Published: |
Harvard University
2014
|
Subjects: | |
Online Access: | http://dissertations.umi.com/gsas.harvard:11363 http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274636 |
Similar Items
-
Optogenetic regulation of endogenous gene transcription in mammals
by: E. S. Omelina, et al.
Published: (2019-03-01) -
Modeling epigenetic modifications in renal development and disease with organoids and genome editing
by: Carmen Hurtado del Pozo, et al.
Published: (2018-11-01) -
Genome Engineering Technology and Its Application in Mammalian Cells
by: Cong, Le
Published: (2014) -
CRISPR-Cas: Development and applications for mammalian genome editing
by: Ran, Fei Ann
Published: (2014) -
CRISPR Cpf1 proteins: structure, function and implications for genome editing
by: Fatemeh Safari, et al.
Published: (2019-05-01)