Optical control of mammalian endogenous transcription and epigenetic states

Optical control of mammalian endogenous transcription and epigenetic states

The dynamic nature of gene expression enables cellular programming, homeostasis and environmental adaptation in living systems. Dissection of causal gene functions in cellular and organismal processes therefore necessitates approaches that enable spatially and temporally precise modulation of gene e...

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Bibliographic Details
Main Author: Brigham, Mark Daniel
Other Authors: Zhang, Feng
Language:en_US
Published: Harvard University 2014
Subjects:
Genetics
Biomedical engineering
Molecular biology
Cas9
CRISPR
epigenetic
optogenetic
TALE
transcription
Online Access:http://dissertations.umi.com/gsas.harvard:11363
http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274636

Internet

http://dissertations.umi.com/gsas.harvard:11363
http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274636

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