A Synthetic Yeast Model for Differentiation and Division of Labor

To maintain high average fitness, populations must effect selection against the deleterious mutations that continuously arise de novo. Theoretical models of mutation-selection balance predict that the maximum tolerable mutation rate is much lower for organisms growing in colonies than for those in w...

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Bibliographic Details
Main Author: Wahl, Mary Elizabeth
Other Authors: Murray, Andrew W.
Language:en_US
Published: Harvard University 2014
Subjects:
Online Access:http://dissertations.umi.com/gsas.harvard:11515
http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274622