Leveraging genetic association data to investigate the polygenic architecture of human traits and diseases
Many human traits and diseases have a polygenic architecture, where phenotype is partially determined by variation in many genes. These complex traits or diseases can be highly heritable and genome-wide association studies (GWAS) have been relatively successful in the identification of associated va...
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| Language: | en_US |
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Harvard University
2014
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| Online Access: | http://dissertations.umi.com/gsas.harvard:11372 http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274191 |